Chloramines exposure during dialysis can lead to which complication?

Chloramines exposure during dialysis can lead to which complication?

• A. Nausea
• B. Dehydration
• C. Hemolysis
• D. Fever

Answer: (C)

Chloramines in dialysate are potent oxidants that can damage red blood cells when they come into contact with blood during dialysis. This oxidative injury weakens the red cell membrane and leads to intravascular hemolysis, releasing hemoglobin into the circulation and potentially causing acute anemia and related complications during a session. That’s why hemolysis is the complication associated with chloramines exposure. Nausea, dehydration, and fever aren’t specific effects of chloramine-induced red cell destruction, though they can occur for other dialysis-related reasons; the defining issue with chloramines is rapid red blood cell breakdown.

Chloramines in dialysate are potent oxidants that can damage red blood cells when they come into contact with blood during dialysis. This oxidative injury weakens the red cell membrane and leads to intravascular hemolysis, releasing hemoglobin into the circulation and potentially causing acute anemia and related complications during a session. That’s why hemolysis is the complication associated with chloramines exposure. Nausea, dehydration, and fever aren’t specific effects of chloramine-induced red cell destruction, though they can occur for other dialysis-related reasons; the defining issue with chloramines is rapid red blood cell breakdown.